PT-141 (Bremelanotide)

For Research Use Only | Not for Human Consumption

Overview

PT-141, also known as Bremelanotide, is a synthetic peptide analogue of alpha-melanocyte-stimulating hormone (α-MSH). It acts as a non-selective agonist of melanocortin receptors (MCR), with particular affinity for MC1R, MC3R, MC4R, and MC5R. Unlike many compounds studied in similar contexts, PT-141 operates centrally via the nervous system rather than through the vascular system.

Molecular Profile

Mechanism of Action

PT-141 functions as a melanocortin receptor agonist. Upon binding, it activates hypothalamic pathways associated with melanocortin signaling. Research has focused on its interaction with MC4R in particular, which has made it a subject of interest in studies examining:

• Melanocortin system signaling pathways
• Central nervous system receptor pharmacology
• Hypothalamic neuroendocrine regulation

Areas of Research Interest

• Melanocortin receptor pharmacology — studying MC3R and MC4R binding affinity and downstream signaling
• Neuroendocrine research — examining central pathway activation related to the melanocortin system
• Inflammatory response studies — preliminary research has explored potential anti-inflammatory properties via melanocortin pathways
• Receptor selectivity profiling — comparing binding characteristics across MCR subtypes

Purity & Quality

• Purity: ≥99% (HPLC verified)
• Peptide content confirmed via Mass Spectrometry
• Certificate of Analysis (CoA) available upon request

Disclaimer

This product is intended for research use only and is not approved for human consumption, therapeutic use, or veterinary application. It is sold strictly for in vitro and laboratory research purposes. This product is not a drug, supplement, or food additive. Researchers must comply with all applicable local, state, and federal regulations governing the use of research peptides.