SS-31 10mg

Product Details

SS-31 (Elamipretide)

SS-31 is a synthetic tetrapeptide with the amino acid sequence D-Arg-2′6′-Dmt-Lys-Phe-NH₂, belonging to the Szeto-Schiller (SS) peptide class. Each vial contains 10mg of lyophilized SS-31 for research purposes only. Third-party 7x tested with Certificate of Analysis (COA) available. Purity: >99%. COA Batches: MPSS001

Description

SS-31 (D-Arg-2′6′-Dmt-Lys-Phe-NH₂), also known as Elamipretide or MTP-131, is a mitochondria-targeted tetrapeptide that selectively concentrates in the inner mitochondrial membrane. It interacts with cardiolipin, a phospholipid essential for the structural integrity of the inner mitochondrial membrane and the function of the electron transport chain. In preclinical and in vitro models, SS-31 has been shown to stabilize cristae architecture, reduce mitochondrial reactive oxygen species (ROS), and support ATP synthesis efficiency.

Its unique alternating aromatic-cationic structure allows it to readily cross lipid bilayers without the need for an electrochemical gradient, distinguishing it from many other mitochondria-targeted compounds studied in research settings.

Specifications

• Unit Size: 10mg (lyophilized powder, single vial)
• Sequence: D-Arg-2′6′-Dmt-Lys-Phe-NH₂
• Molecular Formula: C₃₂H₄₉N₉O₅
• Molecular Weight: ~639.80 Da
• Form: Lyophilized white to off-white powder
• Storage: Store dry at −20°C. After reconstitution, store at 2°C–8°C and use within 48–72 hours. Avoid repeated freeze-thaw cycles.

Application Context

SS-31 is studied in vitro and in preclinical models for its potential effects on:

• Mitochondrial membrane stabilization via cardiolipin interaction
• Reduction of mitochondrial reactive oxygen species (ROS) and oxidative stress
• Preservation of ATP production under conditions of metabolic stress
• Cytoprotection in ischemia-reperfusion injury models
• Mitochondrial dysfunction associated with aging and metabolic disease
• Cardiac, renal, and neurodegenerative research models

Intended Use

This compound is intended strictly for in vitro laboratory research. It is not approved for human or animal use and must not be incorporated into food, drugs, cosmetics, or diagnostic products.

Legal Disclaimer

This product and associated materials have not been evaluated by the FDA. No claims are made regarding diagnosis, treatment, or prevention of disease. Use is restricted to qualified research professionals in certified laboratory settings.

Terms of Sale

By purchasing from Midwest Peptide, the buyer affirms they are a qualified researcher or institution. The purchaser accepts full responsibility for lawful handling, storage, and application of this material. All sales are final.